If you are noticing fine lines, crepey skin, loss of elasticity, under-eye concerns, or changes in skin quality, our Polynucleotide treatments may help support your skin’s natural regeneration process. At Dermal Plus Clinic in Peterborough, we offer personalised Polynucleotide treatments designed to enhance skin rejuvenation, improve hydration, and promote overall skin health, all while maintaining natural-looking results.
Polynucleotides have quickly become one of the most sought-after regenerative aesthetic treatments for those looking to enhance skin quality rather than just add volume. Whether your concerns are related to the delicate under-eye area, facial ageing, neck rejuvenation, or acne scarring, we will create a treatment plan tailored specifically to your individual needs.
What Are Polynucleotides?
Polynucleotides are advanced regenerative aesthetic treatments that work by supporting the skin’s natural repair and renewal processes. They enhance skin quality by encouraging tissue regeneration, supporting hydration, and promoting a healthier skin environment.
Unlike traditional fillers, Polynucleotides are not intended to add volume or alter facial contours. Instead, their focus is on improving the quality, texture, and resilience of the skin.
Many individuals searching for natural skin regeneration treatments are increasingly opting for Polynucleotides because they support long-term skin health while delivering subtle, natural-looking improvements.
Where Do Polynucleotides Come From?
Polynucleotides used in aesthetic medicine are highly purified DNA fragments derived from salmon. Through a sophisticated purification process, these DNA fragments are prepared for use in regenerative skin treatments that support skin repair, hydration, and rejuvenation.
In recent years, the popularity of Polynucleotide treatments has surged online, often referred to as 'Salmon DNA Treatments' or 'Salmon Sperm Facials'. While these terms are prevalent in the media and on social platforms, the treatment itself utilizes highly purified Polynucleotides designed to bolster the skin's natural regenerative processes.
Salmon-derived Polynucleotides are widely used due to their biocompatibility and their potential to improve skin quality, hydration, elasticity, and overall skin health. Unlike dermal fillers, they do not add volume; their goal is to enhance the condition and quality of the skin itself.
Many individuals searching for Salmon DNA treatments, Salmon Sperm Facials, Salmon Sperm Injections, or Polynucleotide treatments are inquiring about the same effective regenerative aesthetic treatment.
At Dermal Plus Clinic, we may utilize leading Polynucleotide products such as PhilArt®, Nucleofill®, Ameela®, Plinest®, Rejuran®, Vitaran®, Mastelli Newest® PN Products, or other clinically appropriate regenerative treatments, depending on your individual needs and treatment goals.



Small amounts of polynucleotides are carefully injected into the treatment area using a series of tiny injections. Treatment usually takes around 30 minutes.
Most patients return to normal daily activities shortly afterwards.
Some mild redness, swelling or bruising may occur but usually settles within a few days.
Many patients notice improvements in skin hydration and radiance within the first few weeks.
Because polynucleotides stimulate your body’s natural repair processes, improvements continue to develop over the following weeks as collagen production increases and tissue regeneration occurs.
The best results are typically seen after completing the recommended course of treatment.
Most patients benefit from an initial course of 3 treatments, performed approximately 2 to 4 weeks apart.
Maintenance treatments every 6 months may be recommended depending on your skin condition and long-term goals.
Although both treatments involve injections, they work in very different ways.
Dermal fillers restore lost volume and enhance facial contours.
Polynucleotides regenerate and repair the skin by stimulating natural healing, collagen production and tissue regeneration without adding volume.
Many patients choose to combine polynucleotides with anti-wrinkle treatments, Profhilo®, Sunekos®, skin boosters, biostimulators, microneedling or PRP as part of a comprehensive skin rejuvenation programme.
At Dermal Plus Clinic, we take a personalised and medically informed approach to regenerative skin treatments.
Our focus is on improving skin health from within by supporting your body’s natural repair mechanisms, helping you achieve healthier, firmer and more youthful-looking skin while maintaining natural facial harmony.
Every treatment plan is tailored to your skin condition, facial anatomy and long-term aesthetic goals.
Please reach us at info@dermalplusclinic.com if you cannot find an answer to your question.
Polynucleotides are regenerative injectable treatments designed to support the skin’s natural repair processes and improve overall skin quality.
Yes. Polynucleotides used in aesthetic treatments are highly purified DNA fragments derived from salmon. These purified Polynucleotides are used to support skin regeneration, hydration and tissue repair.
Yes. “Salmon Sperm Facial” is a popular media term often used to describe Polynucleotide treatments because the Polynucleotides are derived from highly purified salmon DNA. In clinical practice, the treatment is referred to as Polynucleotide therapy and is used to support skin regeneration, hydration and overall skin quality.
No. Dermal fillers are primarily used to restore volume and contour, whereas Polynucleotides focus on improving skin quality, hydration and regeneration.
Yes. Polynucleotides are particularly popular for treating the delicate under-eye area and improving the appearance of tired, ageing skin.
Treatment recommendations vary depending on your skin concerns and goals. A personalised treatment plan will be discussed during your consultation.
Most clients find treatment manageable. We will discuss comfort measures and what to expect before treatment begins.
Yes. Many clients combine Polynucleotides with skin boosters, Profhilo®, anti-wrinkle treatments, microneedling, PRP and other skin rejuvenation treatments as part of a personalised treatment plan.
If you are considering Polynucleotide treatment, Salmon DNA treatment or a Salmon Sperm Facial in Peterborough, Dermal Plus Clinic is here to help. Book your consultation today to discuss your concerns, explore your treatment options and receive a personalised treatment plan tailored to your goals
Book an appointment with us and discover what we can do for you.